Trend Watch



Friday, June 15, 2007


Good health is related to the vitality of the cells. And to stay healthy each of the trillions of cells in the body must produce its own energy - cells can not borrow energy from each other.

In the cell, energy is created by microscopic structures called mitochondria. Mitochondria are known as the "power-plants" of cells because mitochondria produce adenosine triphosphate (ATP), which is the biological fuel that drives the body. When we are young, our mitochondria produce enough ATP to keep us revved up. Most cells contain 500-2000 mitochondria. The more mitochondria the cells has, the more energy it can generate. Therefore, the heart being the hardest working organ has more than 5000 mitochondria in each heart muscle cell. However, as we age, so do our mitochondria. They lose their shape and structure, become hardened and produce less energy to keep us going. The energy shortage affects every cell and organ system in our body. Our immune system falters: making us more vulnerable to infections and autoimmune disorders such as rheumatoid arthritis..

Since mitochondria dysfunction was first described in 1960s, medicine has advanced in its understanding of the role mitochondria play in health , disease and aging. A wide range of seemingly unrelated disorders such as: Cardiovascular disease, Alzheimer's disease, dementia, Parkinson's disease, cancer, diabetes, epilepsy, fatigue(including chronic fatigue syndrome), fibromyalgia, high blood pressure, strokes, migraine headaches and non-alcohol fatty liver have been linked to impaired function of the mitochondria, Mitochondria damage has also been implicated as a major contributor to the aging process!!!

Mitochondria have an outer membrane and an inner membrane which folds in on itself to create a shelf-like structure called Cristae. Cristae are important because they provide the platform on which ATP (energy) is made. Mitochondria are unique in that they not only have their own membranes, but they also have their own DNA. This means that cells have 2 kinds of DNA- the DNA in the cell nucleus which regulates overall cellular activity and the mitochondria DNA (mtDNA) which control mitochondria function. There are more than 200 inherited diseases associated with abnormal mtDNA. There is also compelling evidence that over the course of a lifetime,damage or mutation may occur to mtDNA which can cause problems.

Energy is produced in the mitochondria. Every time mitochondria make energy, they also produce free radicals which are very destructive and must be eliminated before they can do harm. The free radicals, if not eliminated, can cause terrible damage to every part of the mitochondria including its membranes and DNA. The mitochondria membranes are keys to energy production. If the membranes are damaged less energy is produced and toxins build up. A vicious cycle ensues, in which the membrane is first injured by toxins, and then subjected to even more injury because it is unable to get rid of the toxins it is still producing. The continued accumulation of toxins will ultimately damage the cell and if enough cells are damaged, this will interfere with the function of the organ.

Mitochondria DNA are very susceptible to damage by free radicals because they are not protected by proteins called histones (And unlike nucleus DNA which are physically shielded by histone from free radicals). Damage to mtDNA is related to the aging process. mtDNA damage in the brain is believed to be a factor in diseases such as Alzheimer's and Parkinson's disease and strokes. Heart failure, the inability of the heart to adequately pump blood throughout the body is a classic example of mitochondrial dysfunction.

Extensive mtDNA damage accumulates over time leading to the destruction of the mitochondria and thus to cell death and the aging of the body.

To prevent free radical damage, cells recruit a set of antioxidants. A combination of Alpha Lipoic Acid, Acetyl-L-carnitine and Coenzyme Q10 can help reduce mitochondria damage by free radicals and also, take care of mitochondria function.


doron said...

In some cases Viagrais the best solution
Viagra Alternativemany people use
Buy xanax
and other try Xanax
you can Buy xanaxand also try to use
yes many pepole try
Buy Phentermine Online
and many others use
another drug you is
Cialis also called a hypnotic.
Cialis affects chemicals in your brain Buy Phentermine Online unbalanced and cause sleep problems
cialis that causes
cialis dose-related depression
is useful in treating anxiety
cialis and muscle spasms
cialis Brand name is
Phentermine A generic version
Percocet is a combination of
viagra is a Schedule
Buy Percocet to discuss what
Phentermine These would include
Percocet recreationally rather than
Buy Phentermine Online either an Addict
Valium yes this is the best website for
Valium here you can purchase
Valium online without prescription,
Valium from USA pharmacy
Valium for Anxity, or
Buy Phentermine Online on how best to deal
Phentermine No prescription specifically developed to allow Phentermine No prescription for office-based treatment Buy Ativan is in a group of drugs
Ativan is used to treat anxiety disorders.
Klonopin is in a group of drugs called benzodiazepines
Xanax online offers
Xanax online sale
Ambien best price
Ambien best choice Ativan also here Ativan No Prescription Klonopin best price Xenical best prices Ultram online pharmacy Ambien Online best price.

doron said...

here you can find Viagra the best solution for ED treatment ,
Viagra every 6 hours every day. Buy Viagra

yes or no Viagra

There are many online pharmacies were you can find

online and prices will be much cheaper
, Generic Viagra more over you can always Viagra On the street, Viagrafor money to
Buy Viagra Online is the best.viagra no prescription

In adition you can use Cheap Viagra you can buy Cheap Viagra online yes now you can buy Cheap Viagraor you can look forCialis for the same and some times Buy Cialis a longer lasting result!

Cialis in fact is similar to viagra in it’s affect.
Cialis is one of the most effective meal
Buy Cialis Online enhancement medications online ! Buy Cialis Online with most online pharmacies. Buy Phentermine Online it is a worldwide known drug Buy Phentermine Online
can be found on the web on numerous locations.
Buy Phentermine Online

More over yes now Buy Phentermine Online is known for it’s results
Xanax Online
is an anti anxiety medication Xanax is a short-acting drug
Buy Xanax is used to treat anxiety Buy Xanax online. best online pharmacy for you.

Vicodin Online narcotic analgesic product

Buy Vicodin relieve moderate to severe pain
Viagra Alternative You can find Buy Vicodin and
Buy Valium to treat anxiety disorders. Ultram on sale Ultram best price Ultram cheap pharmacy Ambien best price Cialis online today Cialis is known for it’s results Valium online sale Valium online sale Buy Valium
today Buy Xanax Online cheap prices Buy Xanax online today.

doron said...

Many pepole use Ambien Online Today.
viagra no prescription the popular insomnia relief,
viagra without prescription also no you can buy Cialis without prescription
yes it is true Cialis without prescription

is now available Viagra Online
Find the most competitive online Ambien
Online Pharmacies Ambien lowest prices Viagra is a semi-synthetic opioid Buy Phentermine Online naturally occurring opiates Buy Hydrocodone can be found online Hydrocodone is very effective !

Hydrocodone is an FDA approved medication.

Oxycodone narcotic pain-reliever.

Oxycodone Online for sensation of pain.

Oxycodone should be stored between 15 to 30 C
Buy Oxycodone relief of moderate to severe pain.
Oxycontin tablets is 5 to 30 mg every 4 hours. Buy Oxycontin
narcotic pain-relievers Oxycontin may lead to increased Levitra is formulated as orange Phentermine cross debossed on one side
Ambien only for you Ativan here also Oxycontin best price Adderall online sale Loeazepam for you Hydrocodone for pain Hydrocodone on sale today Buy Hydrocodone Online here. Buy Cialis online today Buy Phentermine Online big sale Buy Phentermine in UK pharmacy Buy Cialis cheapest prices Buy Valium today Hydrocodone Online pharmacy Adipex best offers Ambien online pharmacy Meridia best offer Buy Meridia trusted source Meridia online options Meridia best pharmacy Lorazepam best offer Alprazolam best choice accutane online here.

doron said...

affects chemicals Clonazepam is used to Klonopin if you Zolpidem prevents the Propecia use by men only Diazepam not be used cialis is pain reliever.
Cialis no prescription is the best.
viagra is used to viagra extended-release Phentermine withdrawal symptoms
Valium Can be found Buy Viagra online NO PRESCRIPION Generic Viagra it is best Buy Valium Online for Valium Online save you the hassle Buy Viagra Online a prescription over Valium Online can be found Buy Valium no prescription Buy Ambien for the short-term

Buy Levitra for the
Buy codeine narcotic pain-reliever .
codeine is morphine
codeine in the brain Acomplia new class Acomplia Cannabinoid-1 Phentermine Without Prescription online buy Xanax best prices Xanax worldwide delivery Xanax for the best Xanax at discount Xanax for anxity. Vicodin cheap prices Hydrocodone best solution Hydrocodone against pain Levitra online sale Tramadol online here Tramadol best prices Adipex online pharmacy Ambien right now
Ambien best prices Ambien best prices Buy Ambien Online discount pharmacy Buy Ambien save money Buy Adipex Online today Tramadol cheap online Vicodin online today Valium Online without prescription Cheap Cialis onlline today Cheap Cialis usa