Tuesday, August 14, 2007
INTRODUCING ZYBAN: THE FIRST AND ONLY NON-ADDICTIVE, NON NICOTINE ORAL TABLET FOR EASY AND EFFECTIVE SMOKING CESSATION
Brand name is Zyban and the active ingredient is Bupropion. Zyban tablets are indicated for the treatment of nicotine dependence as an aid to smoking cessation. The efficacy of Zyban in the treatment of nicotine dependence has also been demonstrated in populations of smokers with stable cardiovascular disease and /or chronic obstructive pulmonary disease, and in smokers who have previously attempted to quit.
How Zyban act ? In smoker's brain, dopamine(a type of body's neurotransmitter) is associated with cravings for nicotine. Zyban will reduce the URGE by control the activity of dopamine in brain. Beside this, Zyban will also reduce WITHDRAWAL SYMPTOMS of smoker by control the activity of another body's neurotransmitter called Noradregenic neurons. Noradregenic neurons is associated with nicotine withdrawal symptoms.
How about safety profile of Zyban? In clinical trials, the most common side effects were dry mouth and insomnia. Side effects were generally mild and transient. Insomnia may be minimized by avoiding bedtime doses and allowing at least 8 hrs between successive doses. Zyban demonstrated a low rate of discontinuation (8% for Zyban vs 6% for placebo). Zyban is contraindicated in patients with a seizure disorder or a current or prior diagnosis of bulimia or anorexia nervosa. Because the use of bupropion is associated with a dose-dependent risk of seizure, clinicians should not prescribe doses over 300mg/day for smoking cessation. The risk of seizure is also related to patient factors, clinical situation and concurrent medications, which must be considered in selection of patients for therapy with Zyban
Price of Zyban 150mg 60 tablets per box is about RM300. The duration of treatment is about 2 to 3 months. Hence, smokers will spend about RM600-RM900 for treatment. In the long run, it is much more cheaper than cigarettes.
For further info, smokers should discuss with their pharmacist or doctor.
My advice to smokers is SMOKING DOES NOT INVOLVE THE SMOKER ALONE.